IgG4 related disease is an
inflammatory fibrotic systemic disease, which could attack nearly all organs.
Prevalently the disease arise in multiple organs simultaneously or consecutively.
How and why it leads to this disease is largely unknown. In the last ten years the disease has been dicovered so that the actual scientific knowledge
based on a small number of studies and cases by now.
A multicenter studie between clinics in Germany, Austria and Italy should close the gap
on basis of in collaboration-powered database to force the knowledge of disease that htese findings enter into clinical application. So IgG4 treatment could start
at an early stage of disease.